A large international RCT finds automated insulin delivery (MiniMed 670G/770G) improves HbA1c in those above 8% and reduces hypoglycaemia in those at target versus multiple daily injections in type 1 diabetes. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
An RCT finds adding a 2-3 week course of intravenous alprostadil to standard care improves the clinical response rate and lipids in diabetic foot or neuropathy, though the trial was unblinded. PICO summary and commentary.
A 24-week RCT finds Bluetooth-enabled glucometers do not improve glucose control over traditional glucometers in telehealth insulin titration, though they reduce emergency department visits. PICO summary and commentary.
A 24-week RCT finds neither a low-carbohydrate nor a Mediterranean diet significantly changes bone turnover markers in young people with type 1 diabetes, an exploratory null result. PICO summary and commentary.
Summary: In pregnant women with gestational diabetes mellitus (GDM), real-time continuous glucose monitoring (CGM) did not improve the primary composite…
A qualitative study of parents and caregivers of adolescents with type 1 diabetes identifies their needs before transition to adult care, generating four themes to refine a future trial. PICO summary and commentary.
A cost-minimization analysis finds physician-led medication reviews reduce drug count and inappropriate prescriptions in psychiatric outpatients with diabetes while being cost-neutral. PICO summary and commentary.
Summary: In patients with type 2 diabetes experiencing cognitive decline, dapagliflozin and liraglutide treatment significantly improved neuroprotective outcomes compared to…
Summary: In older adults with type 2 diabetes (T2D) and mild cognitive impairment (MCI), hyperbaric oxygen therapy (HBOT) did not…
Summary: In older adults at risk for type 2 diabetes, resistance exercise training significantly improved targeted cognitive function compared to…

