Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Can SGLT2 Inhibitors Reduce Eye Injection Needs in Diabetic Patients with High Blood Pressure?
A small post hoc COMET subgroup finds SGLT2 inhibitor use is associated with about half as many eye injections in diabetic macular edema with high blood pressure, an exploratory finding from 29 patients. PICO summary and commentary.
Can Home-Based Education Improve Diabetes Self-Management?
A small RCT finds home-based diabetes self-management education using Orem's self-care model improves glucose, HbA1c, lipids, blood pressure, and self-care over six weeks. PICO summary and commentary.
How does weight-adjusted waist index predict cardiovascular outcomes in type 2 diabetes?
An observational ACCORD analysis finds higher weight-adjusted waist index is independently associated with more cardiovascular events, heart failure, and mortality in type 2 diabetes, outperforming BMI. PICO summary and commentary.
Low-Carb High-PUFA vs Healthy Nordic Diet for Liver Fat in Type 2 Diabetes (NAFLDiet)
The NAFLDiet trial finds both a low-carb high-PUFA diet and a healthy Nordic diet reduce liver fat versus usual care, but only the Nordic diet also improves weight, HbA1c, triglycerides, and inflammation. PICO summary and commentary.
How Diet Macronutrient Composition Affects Exercise Metabolism in Type 1 Diabetes
A small crossover study finds a high-carb diet shifts exercise fuel toward carbohydrate, while low-carb diets give more time in euglycaemia and less hyperglycaemia around fasted exercise in type 1 diabetes. PICO summary and commentary.