Hypertension

Intensive Below-120 mmHg SBP Control in Diabetes With Prior Stroke: ACCORD-BP Post-Hoc Analysis

A post-hoc ACCORD-BP analysis of 307 patients with type 2 diabetes and prior stroke links intensive SBP control below 120 mmHg to lower MACE risk. PICO summary and expert commentary.

Does the TyG Index Predict Cardiovascular Events in Controlled Hypertension? A SPRINT Post-Hoc Analysis

A post-hoc analysis of the SPRINT trial finds a higher triglyceride-glucose index is associated with greater cardiovascular risk in controlled hypertension, significant only under standard blood pressure treatment. PICO summary and expert commentary.

UKPDS 38: Tight Blood Pressure Control Reduces Stroke by 44% and Diabetes Complications by 24–37% in Type 2 Diabetes

UKPDS 38 demonstrated that tight blood pressure control targeting below 150/85 mmHg reduces stroke by 44%, diabetes-related endpoints by 24%, and microvascular complications by 37% in hypertensive type 2 diabetes over 8.4 years, establishing blood pressure control as a therapeutic target of at least equal macrovascular importance to glycaemic management.

Can Aquatic Exercise Improve Blood Pressure and Fitness in People with Type 2 Diabetes?

An RCT finds five weeks of aquatic exercise improves blood pressure and fitness within-group in type 2 diabetes, but shows no advantage over control. PICO summary and commentary.

Can Family-Based Team Care Improve Outcomes in Hypertension and Diabetes?

An RCT finds interdisciplinary care with family empowerment improves blood pressure, glucose, and quality of life in comorbid hypertension and diabetes. PICO summary and commentary.

Does Community-Based Care Improve Outcomes for HIV, Diabetes, and Hypertension in Sub-Saharan Africa?

The INTE-COMM Lancet trial finds community-based care matches facility care for stable HIV, diabetes, and hypertension in sub-Saharan Africa. PICO summary and expert commentary.

Can SGLT2 Inhibitors Reduce Eye Injection Needs in Diabetic Patients with High Blood Pressure?

A small post hoc COMET subgroup finds SGLT2 inhibitor use is associated with about half as many eye injections in diabetic macular edema with high blood pressure, an exploratory finding from 29 patients. PICO summary and commentary.

How Does Blood Pressure Affect Treatment Response to SGLT2 Inhibitors in Diabetic Macular Edema?

How does blood pressure variability affect heart and kidney health in diabetic and non-diabetic patients?

An ASCOT analysis finds high blood pressure variability is strongly linked to worse cardiovascular and renal outcomes in diabetes, with amlodipine-based therapy reducing events partly via lower variability. PICO summary and commentary.

How does an interdisciplinary care model with family support impact blood pressure and glucose control in patients with hypertension and diabetes?

An RCT finds an interdisciplinary care model with family empowerment improves blood pressure, glucose, and psychosocial outcomes in comorbid hypertension and diabetes. PICO summary and commentary.