A double-blind RCT finds vitamin D improves insulin secretion and HOMA-IR but not fasting glucose in women with prediabetes. PICO summary and clinical expert commentary.
Browsing: Bone & Mineral Metabolism
Osteoporosis, vitamin D, calcium and parathyroid disorders, and bone-health therapeutics.
An RCT finds low-carb and Mediterranean diets do not significantly alter bone turnover markers in young people with type 1 diabetes. PICO summary and expert commentary.
A translational study finds rhPTH(1-34) outperforms alendronate for bone density in diabetic osteoporosis, a low-turnover state. PICO summary and expert commentary for clinicians.
The SLowDOWN phase III RCT finds sitagliptin preserves hip bone density in women with type 2 diabetes. PICO summary and expert commentary for clinicians.
The large D-Health trial finds monthly vitamin D does not prevent hypertension, high cholesterol, or type 2 diabetes in replete older adults. PICO summary and expert commentary.
A randomised trial finds parathyroid ischaemic preconditioning does not reduce hypoparathyroidism after thyroidectomy, with only an exploratory recovery signal. PICO summary and commentary.
A 24-week RCT finds neither a low-carbohydrate nor a Mediterranean diet significantly changes bone turnover markers in young people with type 1 diabetes, an exploratory null result. PICO summary and commentary.
A prospective RCT finds an improved ultrasound-guided RFA protocol with hydrodissection achieves higher clinical success and far less recurrent laryngeal nerve injury in secondary hyperparathyroidism. PICO summary and commentary.
A small RCT finds preoperative calcium and magnesium before thyroidectomy yields numerically lower hypocalcaemia and earlier recovery in Graves’ patients, but the differences were not significant. PICO summary and commentary.
A 52-week phase III RCT finds sitagliptin preserves hip bone density in women with type 2 diabetes, which declines on placebo, but with no effect at other sites. PICO summary and commentary.