A secondary analysis finds women with gestational diabetes reach similar BMI to unaffected women by 3 years postpartum, but their children are twice as likely to be overweight despite comparable diets. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Summary: In patients with type 2 diabetes inadequately controlled on metformin (n=60), adding sitagliptin 100 mg/day to metformin 2000 mg/day…
Summary: In patients with type 2 diabetes inadequately controlled on metformin and glyburide (n=32), sitagliptin add-on therapy for 6 months…
Summary: In adults with type 2 diabetes (n=40), Dibifree dietary phytomix (15 g/day) as add-on therapy significantly reduced HbA1c, fasting/postprandial…
A 7-month crossover trial finds a dietary phytomix (Dibifree) reduces HbA1c and glucose and body fat in type 2 diabetes, with effects sustained after washout, though the study was biotech-affiliated. PICO summary and commentary.
A feasibility pilot finds remote walking coaching is acceptable and mitigates late-pregnancy activity decline in pregnancy hyperglycaemia, with only a preliminary suggestion of neonatal benefit. PICO summary and commentary.
A pilot study finds a computer-vision food-photo app estimates energy intake about as well as 24-hour recall, but both underestimate true intake versus measured expenditure. PICO summary and commentary.
An RCT finds telemedicine-based home care achieves wound healing comparable to in-person care for diabetic foot ulcers, with no significant difference in healing but better self-management. PICO summary and commentary.
A machine-learning analysis of the VISTA trial finds aflibercept better preserves photoreceptor ellipsoid-zone integrity and reduces retinal fluid than laser in diabetic macular edema, with structure correlating with vision. PICO summary and commentary.
The FIVE-STAR mechanistic trial finds finerenone does not change arterial stiffness but reduces albuminuria in diabetic kidney disease, pointing to an intraglomerular-pressure mechanism. PICO summary and commentary.