A 20-week RCT finds adding empagliflozin improves glucose, kidney function, neuropathy symptoms, and nerve conduction velocity in type 2 diabetes, though amplitude and exam scores were unchanged. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A 12-week RCT finds adding sitagliptin to metformin improves fasting glucose, lipids, beta-cell function, and inflammatory cytokines, though HbA1c did not change significantly. PICO summary and commentary.
A subgroup analysis finds adding Control-IQ+ automated insulin delivery to GLP-1 agonist therapy lowers HbA1c and improves time in range without weight gain in insulin-treated type 2 diabetes. PICO summary and commentary.
Summary: In patients with type 2 diabetes mellitus accompanied by cognitive decline, Huayu Tongluo moxibustion therapy targeting specific acupuncture points…
A single-blind RCT finds personalised exercise prescribed from the Chester Step Test reduces glycaemic variability in type 2 diabetes under free-living conditions. PICO summary and commentary.
Summary: In patients with diabetes or prediabetes identified through electronic health records (EHR) recruitment, invitation and recruitment into a physical…
A quasi-experimental Nigerian trial finds a print-based educational module with leaflets and reminders significantly improves diabetes self-care practices versus no intervention. PICO summary and commentary.
Summary: In patients with diabetes receiving care in primary healthcare institutions, personalized patient education using the CAPDCA (collection-assessment-plan-do-check-aggrandizement) iterative model…
A small pilot RCT finds early automated insulin delivery is feasible and well accepted in underresourced youth with new type 1 diabetes, with a non-significant trend toward better glucose control. PICO summary and commentary.
A six-arm trial finds combined training plus astaxanthin best improves oxidative and inflammatory markers in women with type 2 diabetes, but glycaemic gains come from exercise, not the supplement. PICO summary and commentary.