A 12-week trial finds adding resistance exercise to metformin improves glucose control and sleep quality and raises melatonin in elderly type 2 diabetes with sleep disorders. PICO summary and commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
Summary: In 140 older adults diagnosed with sarcopenic obesity according to Asian Working Group for Sarcopenia criteria, TECAR (transfer energy…
Summary: In adults receiving primary care with BMI ≥27 kg/m² and at least one cardiovascular risk factor, enrolled via electronic…
Clinical Context Sleep disturbances and type 2 diabetes share a bidirectional relationship that is often underappreciated in clinical practice. Approximately…
Summary: In 46 obese female college students (body fat ratio ≥30%) from Chongqing Water Resources and Electric Engineering College in…
An RCT finds combined aerobic and resistance training improves modelled insulin secretion and glucose effectiveness more than either alone in men with type 2 diabetes. PICO summary and commentary.
Summary: In adults diagnosed with type 2 diabetes mellitus enrolled in a randomized controlled trial comparing exercise modalities, combined aerobic…
A 12-month RCT finds daily curcumin reduces liver fat, stiffness, and HbA1c and improves inflammatory and antioxidant markers in obese type 2 diabetes with fatty liver. PICO summary and commentary.
An RCT finds adding ezetimibe to metformin raises PPAR-gamma and adiponectin expression and improves insulin resistance in diabetic fatty liver disease, though endpoints are surrogate. PICO summary and commentary.
A multicentre RCT finds adding orlistat to pioglitazone and metformin improves weight, visceral fat, and insulin sensitivity in obese type 2 diabetes, but not HbA1c. PICO summary and commentary.