A 26-week double-blind RCT finds metformin does not reduce insulin resistance in adults with type 1 diabetes, with no change in endogenous glucose production versus placebo. PICO summary and commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
Summary: In young children with Type 1 diabetes mellitus treated with multiple daily insulin injections (MDI), bedtime snacking prior to…
An RCT finds a 12-week school interval jump rope programme improves body composition, fitness, and glucose and lipid markers in overweight adolescents. PICO summary and commentary.
Summary: In patients with type 2 diabetes mellitus accompanied by cognitive decline, Huayu Tongluo moxibustion therapy targeting specific acupuncture points…
A single-blind RCT finds personalised exercise prescribed from the Chester Step Test reduces glycaemic variability in type 2 diabetes under free-living conditions. PICO summary and commentary.
A six-arm trial finds combined training plus astaxanthin best improves oxidative and inflammatory markers in women with type 2 diabetes, but glycaemic gains come from exercise, not the supplement. PICO summary and commentary.
Summary: In adults with overweight or obesity who received oral vancomycin for seven days, oral supplementation with 2′-fucosyllactose (2′-FL) for…
An RCT finds adding a ketogenic diet to dulaglutide improves glucose, lipids, insulin resistance, sleep, and quality of life more than dulaglutide alone in type 2 diabetes. PICO summary and commentary.
Summary: In patients with type 2 diabetes mellitus having baseline HbA1c less than 7.5% (well-controlled diabetes), administration of AntiAGE-Biom probiotic…
Summary: In overweight/obese adults diagnosed with prediabetes, concurrent aerobic and resistance training combined with daily supplementation of microencapsulated persimmon-karonda polyphenols…