Summary:
In overweight prediabetic individuals, mulberry leaf and corn silk extracts delivered in a GOS milk matrix significantly inhibited α-amylase and α-glucosidase activity in vitro and attenuated postprandial glucose excursions compared to placebo/control, though it was associated with no significant adverse side effects reported.
| PICO | Description |
|---|---|
| Population | Overweight individuals diagnosed with prediabetes exhibiting impaired glucose tolerance. |
| Intervention | Administration of mulberry leaf and corn silk extracts incorporated in a galacto-oligosaccharide (GOS) milk matrix. |
| Comparison | Placebo or control treatment without active plant extracts in the same milk matrix. |
| Outcome | Significant inhibition of α-amylase and α-glucosidase enzymatic activities in vitro; attenuation of postprandial blood glucose elevations observed clinically; no major adverse effects reported. |
Source: You Sun, et al. “Effects of Mulberry Leaf and Corn Silk Extracts Against α-Amylase and α-Glucosidase In Vitro and on Postprandial Glucose in Prediabetic Individuals: A Randomized Crossover Trial.” Read article here.
