Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
How Does Mobile Tech Affect Views on Type 2 Diabetes?
A small RCT finds a diabetes self-management app increased patients' perceived disease threat, highlighting digital health's psychological effects. PICO summary and commentary.
Does Dropout History and HbA1c Affect Future Dropout Risk in Diabetes?
A J-DOIT2 secondary analysis finds prior dropout history strongly predicts future dropout from diabetes care, with very high HbA1c a further risk marker. PICO summary and commentary.
Does Curcumin Help Diabetes and Heart Health?
An RCT finds curcumin lowers blood pressure, LDL, and inflammatory markers in type 2 diabetes but does not change HbA1c or glucose. PICO summary and expert commentary.
N-Acetyl-Cysteine as Adjuvant Therapy Accelerates Response in Diabetic Foot Osteomyelitis: Open-Label RCT
An open-label RCT finds N-acetylcysteine speeds the fall in inflammatory markers in diabetic foot osteomyelitis, though clinical outcomes were not measured. PICO summary and commentary.
Antibiotics Unnecessary After Simple Dental Extraction in Well-Controlled Type 2 Diabetes: RCT
An RCT finds prophylactic antibiotics give no benefit after simple tooth extraction in well-controlled type 2 diabetes. PICO summary and expert commentary.
Empagliflozin vs Sitagliptin vs Metformin in Type 2 Diabetes: A Small Three-Arm Trial
A small randomized three-arm trial comparing empagliflozin, sitagliptin, and metformin on glycemic and cardio-metabolic parameters in type 2 diabetes, with significance shown mainly against the metformin arm. PICO summary and expert commentary.
Does a CBT-Based Digital Diet Programme Improve Glycaemic Control in Gestational Diabetes?
A multicentre randomised controlled trial tested whether a cognitive behavioural therapy-based digital dietary programme improved glycaemic control and pregnancy outcomes in gestational diabetes. PICO summary and expert commentary.
Can Statins Help Treat Diabetic Macular Edema?
A small RCT suggests low-dose atorvastatin may aid anti-VEGF therapy for diabetic macular edema more than high-dose, though key endpoints were non-significant. PICO summary and commentary.
Is Aflibercept Alone or Combined with Dexamethasone Better for Diabetic Macular Edema?
A small phase 2 trial finds adding dexamethasone to aflibercept improves diabetic macular edema outcomes with no IOP rise. PICO summary and expert commentary.