An acute crossover infusion study (n=8) found exenatide-glucagon co-infusion raised myocardial glucose uptake and a diastolic strain rate marker in type 2 diabetes. PICO summary and expert commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
An open-label randomised trial testing pharmacist-led collaborative care against usual care on EQ-5D quality of life and HbA1c in 400 patients with diabetes. PICO summary and expert commentary.
A small single-blind RCT (n=60) found a family-centered empowerment program raised diabetes acceptance and self-management questionnaire scores versus usual care, with no glycaemic outcomes measured. PICO summary and expert commentary.
A published BMJ Open study protocol for a planned randomised controlled trial of a COM-B-based exercise intervention in prefrail older adults with diabetes; no efficacy results are reported. PICO summary and expert commentary.
A manufacturer-sponsored secondary analysis and propensity-matched real-world dataset suggest the mySugr digital logbook is associated with better glycaemic control, strongest in those with high baseline HbA1c. PICO summary and expert commentary.
A proof-of-concept cluster randomised trial found the INTEGRATE-D implementation support intervention feasible and acceptable in primary care, with mixed effects on process and clinical outcomes. PICO summary and expert commentary.
A randomised waitlist-controlled trial of a 10-week whole-food plant-based community programme in a predominantly Maori cohort: weight fell by 3.3 kg versus control, but HbA1c, cholesterol and waist changes were not significant. PICO summary and expert commentary.
A small 12-week randomized controlled trial in male recreational athletes with type 2 diabetes found that only the combined diet plus exercise arm improved both glycemic and body-composition markers, with small effect sizes. PICO summary and expert commentary.
A secondary analysis of a gestational-diabetes RCT (122 dyads) found cord-blood lipids, but not maternal lipids after correction, were associated with children’s beta-cell function at age 9. PICO summary and expert commentary.
A single-centre randomised trial testing home telemedicine with Health Belief Model education against conventional care for HbA1c in older adults with type 2 diabetes. PICO summary and expert commentary.