An RCT finds curcumin lowers blood pressure, LDL, and inflammatory markers in type 2 diabetes but does not change HbA1c or glucose. PICO summary and expert commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
An open-label RCT finds N-acetylcysteine speeds the fall in inflammatory markers in diabetic foot osteomyelitis, though clinical outcomes were not measured. PICO summary and commentary.
An RCT finds prophylactic antibiotics give no benefit after simple tooth extraction in well-controlled type 2 diabetes. PICO summary and expert commentary.
A small randomized three-arm trial comparing empagliflozin, sitagliptin, and metformin on glycemic and cardio-metabolic parameters in type 2 diabetes, with significance shown mainly against the metformin arm. PICO summary and expert commentary.
A multicentre randomised controlled trial tested whether a cognitive behavioural therapy-based digital dietary programme improved glycaemic control and pregnancy outcomes in gestational diabetes. PICO summary and expert commentary.
A small RCT suggests low-dose atorvastatin may aid anti-VEGF therapy for diabetic macular edema more than high-dose, though key endpoints were non-significant. PICO summary and commentary.
A small phase 2 trial finds adding dexamethasone to aflibercept improves diabetic macular edema outcomes with no IOP rise. PICO summary and expert commentary.
A 6-month school-based MyBFF@school program improved fasting insulin, HOMA-IR, and HDL-C versus standard schooling in overweight Malaysian children, though BMI still rose. PICO summary and expert commentary.
A post-hoc ACCORD-BP analysis links intensive blood pressure control to lower cardiovascular events in diabetics with prior stroke, without raising recurrent stroke. PICO summary and commentary.
An RCT finds the Diabetes Conversation Map improves knowledge, self-management, and self-efficacy in type 2 diabetes, though without clinical endpoints. PICO summary and commentary.

