A three-arm RCT finds moxibustion plus low-dose tadalafil outperforms either alone for diabetic erectile dysfunction, in an unblinded single-centre setting. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
An RCT finds Wuziyuye Decoction improves sperm motility and concentration over L-carnitine in diabetic men, but without improving pregnancy rates. PICO summary and commentary.
Clinical Context Type 2 diabetes affects male fertility through multiple interconnected mechanisms. Chronic hyperglycemia generates oxidative stress that damages sperm…
Clinical Context Erectile dysfunction (ED) affects 35-75% of men with diabetes mellitus, with prevalence increasing with diabetes duration, poor glycemic…
A small RCT finds a diabetes self-management app increased patients’ perceived disease threat, highlighting digital health’s psychological effects. PICO summary and commentary.
A J-DOIT2 secondary analysis finds prior dropout history strongly predicts future dropout from diabetes care, with very high HbA1c a further risk marker. PICO summary and commentary.
An RCT finds curcumin lowers blood pressure, LDL, and inflammatory markers in type 2 diabetes but does not change HbA1c or glucose. PICO summary and expert commentary.
An open-label RCT finds N-acetylcysteine speeds the fall in inflammatory markers in diabetic foot osteomyelitis, though clinical outcomes were not measured. PICO summary and commentary.
An RCT finds prophylactic antibiotics give no benefit after simple tooth extraction in well-controlled type 2 diabetes. PICO summary and expert commentary.
A small randomized three-arm trial comparing empagliflozin, sitagliptin, and metformin on glycemic and cardio-metabolic parameters in type 2 diabetes, with significance shown mainly against the metformin arm. PICO summary and expert commentary.