A crossover trial finds a Palaeolithic and a diabetes diet give equal glycaemic control when weight is kept stable, suggesting food-group differences alone do not help. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A small single-blind RCT finds adding PEMF therapy to standard care improves wound healing and Charcot-sign resolution in Charcot foot ulcers. PICO summary and commentary.
A BMJ RCT finds time-restricted eating plus exercise before and during pregnancy does not prevent gestational diabetes in high-risk people. PICO summary and commentary.
A lipidomics analysis from the randomised EmDia trial finds empagliflozin remodels plasma lipids in type 2 diabetes, raising beneficial LPCs but also harmful ceramides. PICO summary and commentary.
A placebo-controlled RCT finds metformin does not cut total insulin in type 1 diabetes pregnancy, but reduces mealtime insulin and weight gain in insulin-resistant women. PICO summary and commentary.
Summary: In 126 pregnant women with type 1 diabetes, metformin (titrated to 1000 mg twice daily) as adjunct to standard…
An OPTION post-hoc analysis finds indobufen-based antiplatelet therapy after stenting performs consistently regardless of diabetes status, with a similar bleeding advantage. PICO summary and commentary.
A qualitative realist evaluation finds a text-message programme supports type 1 diabetes care transition mainly via knowledge and motivation, with effects varying by individual. PICO summary and commentary.
Summary: In adults with uncontrolled type 2 diabetes in China, a mobile app-based intervention significantly improved HbA1c and systolic blood…
A multicentre RCT finds a 12-month text-message programme modestly improves HbA1c and blood pressure in poorly controlled type 2 diabetes, but not LDL. PICO summary and commentary.