An RCT finds an eHealth app improves HbA1c at 4 months in older diabetes patients, but usage declines by 8 months, raising durability concerns. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Clinical Context Dexamethasone is widely used perioperatively for prevention of postoperative nausea and vomiting (PONV), reduction of inflammation and edema,…
A double-blind RCT finds a single intraoperative dexamethasone dose raises glucose significantly but below 180 mg/dL in diabetic and non-diabetic patients, supporting nausea prophylaxis. PICO summary and commentary.
Summary: In adults diagnosed with type 2 diabetes receiving standard medical treatment in China, Sanxiao Jiuzhi Gong (SJG) exercise therapy…
A single-centre RCT reports large glycaemic gains from qigong (Sanxiao Jiuzhi Gong) in type 2 diabetes, but the implausibly large effect size warrants caution. PICO summary and commentary.
Summary: In patients with type 2 diabetes exhibiting reduced salivary gland function and associated oral symptoms, low-level laser therapy combined…
A very small interim RCT analysis finds laser and TENS to the salivary glands improve flow and shift the oral microbiome in type 2 diabetes, but evidence is preliminary. PICO summary and commentary.
Clinical Context Type 2 diabetes approximately doubles the risk of dementia and cognitive decline. Diabetic cognitive impairment represents a spectrum…
A clamp study finds tirzepatide preserves the glucagon defence against hypoglycaemia but delays cortisol/noradrenaline and lowers symptom scores, while awareness is unchanged. PICO summary and commentary.
Summary: In patients with type 2 diabetes, stratified by ApoE genotype (E2/E3, E3/E3, E3/E4, and E4/E4 carriers), flaxseed oil supplementation…