Which Add-On Works Better: Empagliflozin or Sitagliptin?
A double-blind RCT finds empagliflozin gives broader cardiometabolic benefit than sitagliptin or metformin as add-on therapy in type 2 diabetes. PICO summary and commentary.
Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Can Gum Treatment Improve Oral Health in Older Adults with Type 2 Diabetes?
An RCT finds a periodontal health programme improves oral hygiene and knowledge in older diabetic patients, but not oral-health quality of life. PICO summary and commentary.
What Affects Gum Treatment Success in Diabetes?
A machine-learning analysis finds lower baseline periodontal severity and HbA1c predict better response to gum therapy in diabetes (random forest AUC 0.83). PICO summary and commentary.
Can CBT for Diet Improve Glucose and Pregnancy Outcomes in Gestational Diabetes?
A multicentre RCT finds a CBT-based dietary app improves postprandial glucose and reduces macrosomia in gestational diabetes. PICO summary and commentary.
Intensive Blood Pressure Control in Diabetes With Prior Stroke: An ACCORD-BP Post-Hoc Analysis
A post-hoc analysis of 307 ACCORD-BP participants with type 2 diabetes and prior stroke links intensive systolic blood pressure control to fewer cardiovascular events. PICO summary and expert commentary.
Can Galician Olive Oil Help Control Blood Sugar?
A 24-week trial finds high-phenolic olive oil reduces insulin resistance in type 2 diabetes, but without changing lipids or blood pressure. PICO summary and commentary.