Summary: In pregnant women diagnosed with hyperglycemia during pregnancy, a behavioral physical activity intervention promoting unsupervised moderate-intensity walking or stepping…
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A feasibility pilot finds a definitive trial of shockwave therapy for diabetic foot ulcers is deliverable, with only a descriptive (not powered) trend toward faster healing at the higher dose. PICO summary and commentary.
An RCT finds low-power laser therapy improves quality-of-life problem scores in diabetic polyneuropathy, but the neuropathy-severity difference between groups was not significant. PICO summary and commentary.
A large RCT finds a nutritionist-designed Mediterranean diet video improves adherence and reduces gestational diabetes from 25.1% to 20.7%, with fewer adverse outcomes. PICO summary and commentary.
A 12-week RCT finds structured yoga improves fasting glucose, HbA1c, and self-care in low-income women with type 2 diabetes, though the glycaemic effect exceeds typical yoga trials. PICO summary and commentary.
A small biomarker RCT finds empagliflozin reduces the renal tubular marker KIM-1 in diabetic heart failure with preserved ejection fraction, with no effect on other biomarkers. PICO summary and commentary.
A 26-week double-blind RCT finds metformin does not reduce insulin resistance in adults with type 1 diabetes, with no change in endogenous glucose production versus placebo. PICO summary and commentary.
A sham-controlled trial finds adding tibial nerve neurodynamic techniques to standard care reduces neuropathy severity and improves quality of life in diabetic neuropathy, though nerve conduction is unchanged. PICO summary and commentary.
A small RCT finds adding sitagliptin or bedtime NPH insulin lowers HbA1c similarly in type 2 diabetes but produces distinct microRNA changes, with sitagliptin affecting a broader set. PICO summary and commentary.
Summary: In adults with Stage II, Grade B periodontitis and type 2 diabetes mellitus, adjunctive local application of hyaluronan-minocycline gel…