A Peplau-theory self-care education programme improved self-reported self-care but not total treatment adherence in 102 elderly patients with diabetes. PICO summary and expert commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A 92-patient randomized trial in Taiwan tested whether 6-month health coaching improves eGFR in type 2 diabetes with early-stage CKD. PICO summary and expert commentary.
A small open-label RCT testing whether real-time CGM feedback added to individualized nutrition therapy improves diet and sleep in prediabetes with overweight or obesity. PICO summary and expert commentary.
A 2×2 cluster RCT in 284 adults with type 2 diabetes and overweight or obesity testing whether nudge-based dietary education and tableware lower HbA1c. PICO summary and expert commentary.
A small single-centre randomised trial testing weight-lowering hypoglycaemic agents plus a high-protein diet and moderate exercise against standard care for diabetes remission in adults with obesity. PICO summary and expert commentary.
A 24-week open-label randomised trial testing pioglitazone plus empagliflozin versus monotherapy for fatty liver in type 2 diabetes. PICO summary and expert commentary.
An acute randomised trial in 57 sedentary adults with type 2 diabetes found a single HIIT session raised flow-mediated dilation more than moderate continuous exercise, while both lowered post-exercise glucose. PICO summary and expert commentary.
A small 12-week factorial feeding trial in prediabetes found that shifting unsaturated fat intake to lunch rather than dinner improved insulin-sensitivity indices, while the primary postprandial glucose outcome was null. PICO summary and expert commentary.
A small secondary analysis of the EDICT randomised trial reports that initial triple therapy was associated with slower carotid intima-media thickness progression and lower liver fat than sequential add-on therapy at matched glycaemic control. PICO summary and expert commentary.
An exploratory randomised trial of an 880 kcal/day total diet replacement programme in 17 adults with compensated MASLD cirrhosis found safe weight loss and reduced liver fat, but cannot confirm efficacy. PICO summary and expert commentary.