A single-centre Shanghai RCT found a family-support self-management programme raised self-management behaviour scores in type 2 diabetes, while HbA1c and other biochemical markers did not improve significantly. PICO summary and expert commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A secondary analysis of the CORDIOPREV trial reports that a lower baseline neutrophil count is associated with type 2 diabetes remission in patients with coronary heart disease following a Mediterranean diet. PICO summary and expert commentary.
A randomized crossover trial in 75 young adults found acute sucralose raised hypothalamic blood flow and, versus sucrose, increased hunger, with no hunger difference versus water. PICO summary and expert commentary.
Summary: In 70 Iranian women with newly diagnosed PCOS (aged 15–40 years), 330 mg of Salvia officinalis extract daily for…
A 3-month randomised controlled trial found that a 10-hour time-restricted eating window did not alter mitochondrial bioenergetics in blood cells of adults at high type 2 diabetes risk. PICO summary and expert commentary.
A 2-year cluster RCT in India found a family-based, health-worker-delivered programme cut adult body weight by an adjusted 2.61 kg versus enhanced usual care. PICO summary and expert commentary.
Summary: In Chinese adults with type 2 diabetes, a 6-month low-calorie diet achieved diabetes remission in 56% of participants, with…
An RCT finds lower-limb resistance training improves glycaemic control and quality of life in diabetic foot ulcer patients, but not wound healing. PICO summary and commentary.
Pooled RCTs find mild sleep restriction lowers TSH in women specifically, with no effect overall and no change in FT4. PICO summary and expert commentary.
Summary: In healthy adult volunteers (Japanese n=20-21, non-Japanese n=20-21), single-dose cilofexor 100 mg or firsocostat 20 mg showed higher plasma…