An RCT finds an eight-session lifestyle health-promotion programme improves health behaviours and beliefs in type 2 diabetes, on self-report measures. PICO summary and commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
Summary: In patients undergoing laparoscopic sleeve gastrectomy (LSG), a combination of preoperative HDL-C and visceral adipose tissue (VAT) significantly predicted…
A crossover trial finds a moderate-FODMAP diet plus metformin lowers postprandial glucose and raises GLP-1 in prediabetes, with microbiota shifts. PICO summary and commentary.
A multicentre RCT finds a CBT-based dietary app improves postprandial glucose and reduces macrosomia in gestational diabetes. PICO summary and commentary.
An RCT finds home dual-task exercise improves executive function and HDL in diabetic postmenopausal women, but does not change the TNF/IL-10 balance or glucose. PICO summary and commentary.
A SURMOUNT-1 analysis finds tirzepatide improves insulin sensitivity (mostly via weight loss) and beta-cell function (mostly drug-driven) in obesity without diabetes. PICO summary and commentary.
A SURMOUNT-1 analysis finds 90% of early non-responders to tirzepatide still reached 5% weight loss by week 72, supporting extending treatment. PICO summary and commentary.
A 24-week trial finds high-phenolic olive oil reduces insulin resistance in type 2 diabetes, but without changing lipids or blood pressure. PICO summary and commentary.
A crossover trial finds the Omnipod 5 Activity feature reduces insulin and blunts exercise glucose drops in type 1 diabetes, though hypoglycemia rates were unchanged. PICO summary and commentary.
A double-blind RCT finds nanocurcumin does not improve pain or neuropathy outcomes in diabetic peripheral neuropathy. PICO summary and expert commentary.