Summary: In individuals with type 2 diabetes, cinnamon supplementation significantly reduced anthropometric measurements compared to placebo, though it was not…
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A 12-week trial finds chicory-root fibre improves whole-body insulin sensitivity and lowers triglycerides in obesity, with butyrate-producing gut bacteria enriched. PICO summary and commentary.
A 54-patient randomized trial testing intermittent Islamic fasting added to lifestyle modification against lifestyle modification alone in adults with metabolic syndrome, with greater percent-change improvements in weight and metabolic markers in the fasting arm. PICO summary and expert commentary.
“`html Summary: In patients with type 2 diabetes mellitus, a combined exercise program significantly reduced abdominal fat and improved sleep…
A small crossover trial found almond milk offered no postprandial glycaemic benefit over 2% cow milk in adults with type 2 diabetes, with the primary glucose endpoint null. PICO summary and expert commentary.
A small pilot finds curcumin lowers HbA1c in prediabetic older adults, but without changing weight, lipids, or overall gut microbiome diversity. PICO summary and commentary.
A single-centre randomised controlled trial testing multidisciplinary multifactorial care against standard care in 192 adults with type 2 diabetes, with a modest HbA1c reduction and improved eGFR. PICO summary and expert commentary.
A crossover trial finds orange juice with breakfast raises glucose no more than whole orange or a sugary drink of matched sugar in well-controlled type 2 diabetes. PICO summary and commentary.
An ACCORD analysis finds a triglyceride-glucose-waist index independently predicts cardiovascular events and mortality in type 2 diabetes, beating TyG alone. PICO summary and commentary.
In a phase 2 trial, the antisense DGAT2 inhibitor ION224 met the primary histological endpoint in MASH with fibrosis at week 51, though benefit remains preliminary and per-protocol. PICO summary and expert commentary.