A small CGM crossover study finds 30 g/day defatted fenugreek flakes reduces 24-hour glucose excursions and variability in type 2 diabetes. PICO summary and commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A secondary analysis finds probiotics plus omega-3 improve beta-cell function only marginally versus baseline and not versus placebo when adjusted, though secondary metabolic markers improve. PICO summary and commentary.
A prespecified BRIGHT-4 subgroup analysis finds bivalirudin reduces death or major bleeding versus heparin in lower-BMI STEMI patients but not higher-BMI, with a significant interaction. PICO summary and commentary.
Summary: In trained adult athletes participating in a controlled energy availability study, short-term low energy availability (LEA) at 15 kcal·kg…
Summary: In adults diagnosed with type 2 diabetes receiving standard medical treatment in China, Sanxiao Jiuzhi Gong (SJG) exercise therapy…
A single-centre RCT reports large glycaemic gains from qigong (Sanxiao Jiuzhi Gong) in type 2 diabetes, but the implausibly large effect size warrants caution. PICO summary and commentary.
A double-blind RCT finds a single high dose of vitamin D before an ultramarathon favourably shifts bone turnover markers, though mega-dosing remains experimental. PICO summary and commentary.
Summary: In patients with type 2 diabetes, stratified by ApoE genotype (E2/E3, E3/E3, E3/E4, and E4/E4 carriers), flaxseed oil supplementation…
An open-label RCT finds 24 g/day fibre cereal improves the FIB-4 fibrosis index and HbA1c in type 2 diabetes with fatty liver, without weight change. PICO summary and commentary.
A 5-week RCT finds aquatic exercise improves blood pressure and function within-group in type 2 diabetes, but without significant differences versus controls. PICO summary and commentary.

