An RCT finds seated exercise gives greater pain relief, knee function, and physical quality of life than standing exercise in obese women with knee osteoarthritis, while standing favours mental quality of life. PICO summary and commentary.
Browsing: Obesity & Weight Management
An RCT finds combining HIIT with asparagus root extract improves oxidative, inflammatory, and lipid markers in overweight young adults, while the extract alone raises a pro-oxidant marker. PICO summary and commentary.
Summary: In individuals at risk for dementia with cardiometabolic features, intentional, non-pharmacological weight loss significantly reduced dementia risk as detected…
A prespecified SELECT analysis finds semaglutide’s cardiovascular benefit is largely independent of weight loss, with only a third mediated by waist reduction. PICO summary and commentary.
SYNCHRONIZE-1 reports baseline characteristics of a phase 3 survodutide obesity trial; efficacy results are pending. PICO summary and expert commentary.
A SURMOUNT-5 analysis finds tirzepatide and semaglutide improve physical quality of life in obesity, with neither improving mental-health scores. PICO summary and expert commentary.
An RCT finds HIIT combined with a dietitian-designed diet improves body composition, cardiovascular and endothelial function, and lipids more than exercise alone in overweight children. PICO summary and commentary.
Summary: In young patients with obesity and generalized gingivitis, systemic administration of cerium oxide nanoparticles (Cerera) for 10 days following…
Summary: In adults with obesity and/or type 2 diabetes (mean age 47.9 years, 74% female) referred for physical activity intervention,…
An RCT finds a gamified digital activity programme increases daily steps more than supervised face-to-face exercise in obesity, but with marked individual variability and no clinical-outcome or cost difference. PICO summary and commentary.