Summary: In overweight/obese adults diagnosed with prediabetes, concurrent aerobic and resistance training combined with daily supplementation of microencapsulated persimmon-karonda polyphenols…
Browsing: Obesity & Weight Management
Evidence summaries for obesity and weight management, including lifestyle trials, pharmacotherapy, bariatric/metabolic outcomes, cardiometabolic risk, and long-term safety.
Summary: In children and adolescents (n=179) with overweight or obesity enrolled in a healthy lifestyle programme in New Zealand, exposure…
Summary: In 140 older adults diagnosed with sarcopenic obesity according to Asian Working Group for Sarcopenia criteria, TECAR (transfer energy…
Summary: In adults receiving primary care with BMI ≥27 kg/m² and at least one cardiovascular risk factor, enrolled via electronic…
Summary: In 46 obese female college students (body fat ratio ≥30%) from Chongqing Water Resources and Electric Engineering College in…
A multicentre RCT finds adding orlistat to pioglitazone and metformin improves weight, visceral fat, and insulin sensitivity in obese type 2 diabetes, but not HbA1c. PICO summary and commentary.
An analysis of the overall-negative MIND diet trial finds a cognitive benefit only in older adults with BMI 35 or above, a hypothesis-generating subgroup signal. PICO summary and commentary.
A prespecified BRIGHT-4 subgroup analysis finds bivalirudin reduces death or major bleeding versus heparin in lower-BMI STEMI patients but not higher-BMI, with a significant interaction. PICO summary and commentary.
A small 6-week RCT finds barley-based cereal improves weight, glycated albumin, and LDL versus corn cereal in overweight adults. PICO summary and commentary.
Summary: In 126 pregnant women with type 1 diabetes, metformin (titrated to 1000 mg twice daily) as adjunct to standard…