Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
How Does Prebiotic Intervention Affect Glycemic Control and Gut Microbiome in Indian Children with Type 1 Diabetes?
A pilot RCT finds prebiotic inulin enriches SCFA-producing gut bacteria but does not improve HbA1c in Indian children with type 1 diabetes. PICO summary and expert commentary.
Can a Ketogenic Diet Enhance the Effects of Dulaglutide in Type 2 Diabetes?
An RCT finds adding a ketogenic diet to dulaglutide improves glucose, lipids, and insulin resistance in type 2 diabetes. PICO summary and clinical expert commentary.
Can Metformin Prevent Steroid-Induced High Blood Sugar and Baby Low Blood Sugar?
An RCT finds a short metformin course after antenatal betamethasone lowers maternal glucose and halves neonatal hypoglycaemia. PICO summary and expert commentary for clinicians.
Do Low-Carb or Mediterranean Diets Affect Bone Health in Young People with Type 1 Diabetes?
An RCT finds low-carb and Mediterranean diets do not significantly alter bone turnover markers in young people with type 1 diabetes. PICO summary and expert commentary.
Does adding dexamethasone during vitrectomy improve outcomes in diabetic retinal detachment?
An RCT finds an intravitreal dexamethasone implant during diabetic vitrectomy cuts reproliferation and improves vision. PICO summary and expert commentary for clinicians.
Can Lifestyle-Based Interventions Improve Habits in Type 2 Diabetes?
An RCT finds a structured lifestyle-based programme improves health behaviours and beliefs in type 2 diabetes, though without glycaemic endpoints. PICO summary and expert commentary.
Can Exercise and Broccoli Improve Heart and Metabolic Health in Type 2 Diabetes?
An RCT finds combining exercise with broccoli sprout supplementation improves apolipoproteins in type 2 diabetes, mainly driven by exercise. PICO summary and expert commentary.
Does Dapagliflozin Improve Heart Blood Flow Long-Term in Type 2 Diabetes?
The DAPAHEART follow-up finds 4 years of dapagliflozin improves coronary flow reserve and reduces epicardial fat in type 2 diabetes. PICO summary and expert commentary.
Can Placenta-Derived Cells Heal Diabetic Foot Ulcers with Poor Circulation?
A phase 2 RCT finds placenta-derived cells improve diabetic foot ulcer closure in the peripheral artery disease subgroup. PICO summary and expert commentary for clinicians.