An RCT finds a short metformin course after antenatal betamethasone lowers maternal glucose and halves neonatal hypoglycaemia. PICO summary and expert commentary for clinicians.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
An RCT finds low-carb and Mediterranean diets do not significantly alter bone turnover markers in young people with type 1 diabetes. PICO summary and expert commentary.
An RCT finds an intravitreal dexamethasone implant during diabetic vitrectomy cuts reproliferation and improves vision. PICO summary and expert commentary for clinicians.
An RCT finds a structured lifestyle-based programme improves health behaviours and beliefs in type 2 diabetes, though without glycaemic endpoints. PICO summary and expert commentary.
An RCT finds combining exercise with broccoli sprout supplementation improves apolipoproteins in type 2 diabetes, mainly driven by exercise. PICO summary and expert commentary.
The DAPAHEART follow-up finds 4 years of dapagliflozin improves coronary flow reserve and reduces epicardial fat in type 2 diabetes. PICO summary and expert commentary.
A phase 2 RCT finds placenta-derived cells improve diabetic foot ulcer closure in the peripheral artery disease subgroup. PICO summary and expert commentary for clinicians.
An RCT finds adding sitagliptin to standard care improves diabetic foot ulcer healing via an EPC/SDF-1α mechanism. PICO summary and expert commentary for clinicians.
An RCT finds five weeks of aquatic exercise improves blood pressure and fitness within-group in type 2 diabetes, but shows no advantage over control. PICO summary and commentary.
An RCT finds low-dose dexmedetomidine steadies perioperative glucose in diabetic surgery while higher doses worsen it. PICO summary and expert commentary for clinicians.