The DAPAHEART follow-up finds 4 years of dapagliflozin improves coronary flow reserve and reduces epicardial fat in type 2 diabetes. PICO summary and expert commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A phase 2 RCT finds placenta-derived cells improve diabetic foot ulcer closure in the peripheral artery disease subgroup. PICO summary and expert commentary for clinicians.
An RCT finds adding sitagliptin to standard care improves diabetic foot ulcer healing via an EPC/SDF-1α mechanism. PICO summary and expert commentary for clinicians.
An RCT finds five weeks of aquatic exercise improves blood pressure and fitness within-group in type 2 diabetes, but shows no advantage over control. PICO summary and commentary.
An RCT finds low-dose dexmedetomidine steadies perioperative glucose in diabetic surgery while higher doses worsen it. PICO summary and expert commentary for clinicians.
An RCT finds 660 nm photobiomodulation reduces diabetic foot ulcer area but does not beat 904 nm; ≥8 J/cm² works best. PICO summary and expert commentary for clinicians.
An RCT finds interdisciplinary care with family empowerment improves blood pressure, glucose, and quality of life in comorbid hypertension and diabetes. PICO summary and commentary.
A translational study finds rhPTH(1-34) outperforms alendronate for bone density in diabetic osteoporosis, a low-turnover state. PICO summary and expert commentary for clinicians.
A 12-month RCT finds curcumin 1500 mg daily reduces liver fat, stiffness, and HbA1c in obese type 2 diabetes with MASLD. PICO summary and expert commentary for clinicians.
An RCT secondary analysis finds probiotics plus omega-3 do not significantly improve beta-cell function versus placebo in type 2 diabetes. PICO summary and expert commentary.