Can Moxibustion Help Memory in Type 2 Diabetes?
An RCT finds higher-temperature (44-46C) moxibustion improves cognition and HbA1c more than lower temperatures in type 2 diabetes, though fasting glucose was unchanged. PICO summary and commentary.
Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Exercise Plus Broccoli Sprouts Improves Atherogenic Lipoproteins in Type 2 Diabetes: 12-Week RCT
A four-arm RCT finds exercise plus broccoli sprouts improves apolipoproteins in men with type 2 diabetes, but the benefit is mainly exercise-driven. PICO summary and commentary.
Does Time-Restricted Eating Improve Mood and Quality of Life in Type 2 Diabetes?
A secondary analysis finds neither time-restricted eating nor calorie restriction changes mood or quality of life in type 2 diabetes, suggesting they are psychologically neutral. PICO summary and commentary.
Does Citrulline Improve Blood Flow and Strength in Older Adults with Diabetes?
A small crossover trial finds citrulline improves microvascular function and calf muscle strength in older adults with type 2 diabetes. PICO summary and commentary.
Do Food Vouchers Improve Diets in Diabetic Patients?
An RCT finds a grocery voucher modestly increases fruit and cuts refined grains in food-insecure diabetic patients, but does not significantly change diet quality or HbA1c. PICO summary and commentary.
Do Diet Changes Improve Blood Sugar Without Weight Loss?
A crossover trial finds a Palaeolithic and a diabetes diet give equal glycaemic control when weight is kept stable, suggesting food-group differences alone do not help. PICO summary and commentary.
PEMF Therapy Enhances Wound Healing and Bone Regeneration in Charcot Foot Ulcers: RCT
A small single-blind RCT finds adding PEMF therapy to standard care improves wound healing and Charcot-sign resolution in Charcot foot ulcers. PICO summary and commentary.
Time-Restricted Eating and Exercise Before Pregnancy Did Not Prevent Gestational Diabetes: BEFORE THE BEGINNING Trial
A BMJ RCT finds time-restricted eating plus exercise before and during pregnancy does not prevent gestational diabetes in high-risk people. PICO summary and commentary.
Empagliflozin Alters Plasma Lipidome in Type 2 Diabetes: EmDia Trial Lipidomics Analysis
A lipidomics analysis from the randomised EmDia trial finds empagliflozin remodels plasma lipids in type 2 diabetes, raising beneficial LPCs but also harmful ceramides. PICO summary and commentary.
Does Metformin Help in Type 1 Diabetes Pregnancy? A Placebo-Controlled Trial
A placebo-controlled RCT finds metformin does not cut total insulin in type 1 diabetes pregnancy, but reduces mealtime insulin and weight gain in insulin-resistant women. PICO summary and commentary.