Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
How does continuous glucose monitoring improve glycemic control in adults with type 2 diabetes on basal insulin?
A 3-month MOBILE analysis finds CGM lowers HbA1c more than fingerstick monitoring and reduces hypoglycaemia in basal-insulin-treated type 2 diabetes, with benefits within a week. PICO summary and commentary.
Comparing Two Extended-Bolus Methods for Mixed Meals in Pediatric Type 1 Diabetes
A crossover trial finds two extended-bolus algorithms both control post-meal glucose in adolescent type 1 diabetes; the simpler Sieradzki method trends better but not significantly. PICO summary and commentary.
Fully Closed-Loop Insulin-Pramlintide System Without Carb Counting: Pilot Study Results
A small pilot finds a fully closed-loop insulin-pramlintide system without carb counting achieves time in range similar to carb-counted control, with a non-significant hypoglycaemia signal. PICO summary and commentary.
Food Order Strategy: Vegetables First, Then Protein, Then Carbs for Better Blood Sugar
A crossover CGM study in healthy young women finds eating vegetables and protein before carbohydrates, in five smaller meals, reduces glucose variability and peaks. PICO summary and commentary.
Can a Tailored Intervention Improve Diabetes Outcomes for Chinese Americans?
A pilot RCT finds a culturally and linguistically tailored programme improves self-efficacy, diabetes distress, and diet adherence in Chinese Americans with type 2 diabetes. PICO summary and commentary.