A small pilot finds a fully closed-loop insulin-pramlintide system without carb counting achieves time in range similar to carb-counted control, with a non-significant hypoglycaemia signal. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Summary: In adults with type 1 diabetes requiring insulin therapy, a fully closed-loop system combining automated insulin and pramlintide delivery…
A crossover CGM study in healthy young women finds eating vegetables and protein before carbohydrates, in five smaller meals, reduces glucose variability and peaks. PICO summary and commentary.
Summary: In adult patients with diabetic foot ulcers requiring wound closure, application of polylactic acid (PLA) dermal matrix dressings demonstrated…
Summary: In pregnant women diagnosed with gestational diabetes mellitus from both culturally and linguistically diverse (CALD) and non-CALD backgrounds, a…
Summary: In children diagnosed with type 1 diabetes mellitus requiring prandial insulin therapy, advanced insulin dose calculation algorithms designed to…
A pilot RCT finds a culturally and linguistically tailored programme improves self-efficacy, diabetes distress, and diet adherence in Chinese Americans with type 2 diabetes. PICO summary and commentary.
A 6-month RCT finds calcitriol lowers inflammation and tubular-injury biomarkers in early diabetic kidney disease, but the albuminuria reduction was not statistically significant. PICO summary and commentary.
A 12-week trial finds adding resistance exercise to metformin improves glucose control and sleep quality and raises melatonin in elderly type 2 diabetes with sleep disorders. PICO summary and commentary.
📚 Part of the GLP-1 Receptor Agonists Trial Guide — every landmark trial in one place. Clinical Context This landmark…