A small CGM crossover study finds 30 g/day defatted fenugreek flakes reduces 24-hour glucose excursions and variability in type 2 diabetes. PICO summary and commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
Clinical Context Hypoglycemia poses particular dangers in elderly patients with diabetes. The physiological warning symptoms that alert younger patients to…
Summary: In elderly individuals with type 2 diabetes at risk of hypoglycemia at outpatient diabetes clinics in Jordan, the SUGAR…
A double-blind dose-response trial finds red and infrared laser all reduce diabetic foot ulcer size over time but with no significant difference between groups; 8-12 J/cm2 gave more responders. PICO summary and commentary.
A secondary analysis finds probiotics plus omega-3 improve beta-cell function only marginally versus baseline and not versus placebo when adjusted, though secondary metabolic markers improve. PICO summary and commentary.
A small RCT finds adding a dexamethasone implant to vitrectomy with silicone oil tamponade reduces recurrent membranes and improves vision in proliferative diabetic retinopathy with detachment. PICO summary and commentary.
A single-blind RCT finds pictorial foot-care education substantially improves knowledge and practice scores in people with type 2 diabetes in Karachi slums. PICO summary and commentary.
A combined mouse and clinical study finds the anabolic agent rhPTH(1-34) reverses low bone turnover in type 2 diabetic bone disease and improves bone density more than alendronate. PICO summary and commentary.
Summary: In patients with diabetic foot ulcers (DFU), topical ozonated olive oil significantly improved wound healing, quality of life, glycemic…
A small mechanistic trial in youth-onset type 2 diabetes finds metformin and liraglutide shift gut bacteria and bile acids; bile-acid metabolites, not microbiota shifts, track with glucose. PICO summary and commentary.