A GRADE substudy finds adults adding a second drug to metformin maintain high medication adherence over 3 years with small between-drug differences, while lower adherence robustly predicts worse glycaemic control. PICO summary and commentary.
Browsing: Diabetes & Glycaemic Control
Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
An RCT finds adding oral agents to short-term intensive insulin improves early glucose control and beta-cell measures in new type 2 diabetes, but does not improve 12-month remission rates. PICO summary and commentary.
A feasibility study finds explicit HbA1c target-setting is acceptable to patients and clinicians, with no between-group difference but improved distress and self-efficacy across groups. PICO summary and commentary.
A 24-week RCT finds Bluetooth-enabled glucometers do not improve glucose control over traditional glucometers in telehealth insulin titration, though they reduce emergency department visits. PICO summary and commentary.
Summary: In pregnant women with gestational diabetes mellitus (GDM), real-time continuous glucose monitoring (CGM) did not improve the primary composite…
A small RCT finds home-based diabetes self-management education using Orem’s self-care model improves glucose, HbA1c, lipids, blood pressure, and self-care over six weeks. PICO summary and commentary.
Summary: In adults with type 2 diabetes (n=40), Dibifree dietary phytomix (15 g/day) as add-on therapy significantly reduced HbA1c, fasting/postprandial…
A 7-month crossover trial finds a dietary phytomix (Dibifree) reduces HbA1c and glucose and body fat in type 2 diabetes, with effects sustained after washout, though the study was biotech-affiliated. PICO summary and commentary.
A feasibility pilot finds remote walking coaching is acceptable and mitigates late-pregnancy activity decline in pregnancy hyperglycaemia, with only a preliminary suggestion of neonatal benefit. PICO summary and commentary.
Summary: In pregnant women diagnosed with hyperglycemia during pregnancy, a behavioral physical activity intervention promoting unsupervised moderate-intensity walking or stepping…