An RCT finds low-dose dexmedetomidine steadies perioperative glucose in diabetic surgery while higher doses worsen it. PICO summary and expert commentary for clinicians.
Browsing: Diabetes & Glycaemic Control
Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
A cluster RCT finds a structured personalised education model markedly improves glycaemic control in type 2 diabetes, though intensity limits generalisability. PICO summary and commentary.
A feasibility analysis finds a culturally tailored dietary intervention engages diverse women with gestational diabetes equally, but does not change measured intake. PICO summary and commentary.
A crossover RCT finds a specific probiotic strain modestly improves fasting glycaemia and beta-cell indices in metformin-treated type 2 diabetes. PICO summary and expert commentary.
A pilot RCT finds a culturally tailored WeChat-delivered programme improves self-efficacy and reduces diabetes distress in Chinese Americans with type 2 diabetes. PICO summary and commentary.
A small crossover trial finds a mulberry leaf and corn silk functional milk lowers postprandial glucose only in an overweight prediabetic subgroup. PICO summary and expert commentary.
The Look AHEAD trial demonstrated that intensive lifestyle intervention targeting weight loss in overweight or obese adults with type 2 diabetes did not reduce cardiovascular events over 9.6 years despite clear differences in weight, fitness, and glycaemic control, establishing a critical negative result that informed the rationale for pharmacological obesity treatment with greater weight loss efficacy.
A three-year follow-up finds most people who reached diabetes remission via intermittent calorie restriction maintained it without ongoing intervention. PICO summary and commentary.
A proof-of-concept crossover study finds a fat preload does not change postprandial glucose after sleeve gastrectomy, but raises insulin. PICO summary and commentary.
Summary: In adults with type 2 diabetes, various glucose-lowering medications as studied in the GRADE trial showed small differences in…