Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
A pilot RCT finds a culturally tailored WeChat-delivered programme improves self-efficacy and reduces diabetes distress in Chinese Americans with type 2 diabetes. PICO summary and commentary.
A small crossover trial finds a mulberry leaf and corn silk functional milk lowers postprandial glucose only in an overweight prediabetic subgroup. PICO summary and expert commentary.
The Look AHEAD trial demonstrated that intensive lifestyle intervention targeting weight loss in overweight or obese adults with type 2 diabetes did not reduce cardiovascular events over 9.6 years despite clear differences in weight, fitness, and glycaemic control, establishing a critical negative result that informed the rationale for pharmacological obesity treatment with greater weight loss efficacy.
A three-year follow-up finds most people who reached diabetes remission via intermittent calorie restriction maintained it without ongoing intervention. PICO summary and commentary.
A proof-of-concept crossover study finds a fat preload does not change postprandial glucose after sleeve gastrectomy, but raises insulin. PICO summary and commentary.
A GRADE substudy finds adults adding a second drug to metformin maintain high medication adherence over 3 years with small between-drug differences, while lower adherence robustly predicts worse glycaemic control. PICO summary and commentary.
An RCT finds adding oral agents to short-term intensive insulin improves early glucose control and beta-cell measures in new type 2 diabetes, but does not improve 12-month remission rates. PICO summary and commentary.
A feasibility study finds explicit HbA1c target-setting is acceptable to patients and clinicians, with no between-group difference but improved distress and self-efficacy across groups. PICO summary and commentary.
A 24-week RCT finds Bluetooth-enabled glucometers do not improve glucose control over traditional glucometers in telehealth insulin titration, though they reduce emergency department visits. PICO summary and commentary.
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