Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
A 12-week trial finds adding resistance exercise to metformin improves glucose control and sleep quality and raises melatonin in elderly type 2 diabetes with sleep disorders. PICO summary and commentary.
A crossover RCT finds a specific Bifidobacterium animalis probiotic blunts the rise in glucose and insulin resistance and raises immunoglobulins in type 2 diabetes, with modest adjunctive benefit. PICO summary and commentary.
An RCT finds intraoperative dexmedetomidine reduces glucose variability, insulin requirements, and CRP in diabetic off-pump CABG patients, though endpoints are surrogate. PICO summary and commentary.
A crossover RCT finds weekly structured telehealth modestly lowers HbA1c and improves time in range in poorly controlled paediatric type 1 diabetes, without more hypoglycaemia. PICO summary and commentary.
A small CGM crossover study finds 30 g/day defatted fenugreek flakes reduces 24-hour glucose excursions and variability in type 2 diabetes. PICO summary and commentary.
An RCT finds topical ozonated olive oil improves diabetic foot ulcer healing, quality of life, and HbA1c, though lipids and IL-6/TNF-a are unchanged despite the title. PICO summary and commentary.
A four-arm RCT finds only low-dose dexmedetomidine improves perioperative glucose in type 2 diabetes, while higher doses raise it, showing a dose-dependent effect. PICO summary and commentary.
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