Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
A 12-week RCT finds adding sitagliptin to metformin improves fasting glucose, lipids, beta-cell function, and inflammatory cytokines, though HbA1c did not change significantly. PICO summary and commentary.
A small RCT finds a digital-twin decision-support system with a simulation-assisted bolus calculator improves time in range and reduces hypoglycaemia in type 1 diabetes. PICO summary and commentary.
A small open-label RCT finds early NPH insulin plus infusion speeds resolution of severe DKA and delays rebound hyperglycaemia, without a significant difference in hypoglycaemia. PICO summary and commentary.
A 3-month MOBILE analysis finds CGM lowers HbA1c more than fingerstick monitoring and reduces hypoglycaemia in basal-insulin-treated type 2 diabetes, with benefits within a week. PICO summary and commentary.
A crossover CGM study in healthy young women finds eating vegetables and protein before carbohydrates, in five smaller meals, reduces glucose variability and peaks. PICO summary and commentary.
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