Summary: In patients with type 2 diabetes exhibiting reduced salivary gland function and associated oral symptoms, low-level laser therapy combined…
Browsing: PICO
A very small interim RCT analysis finds laser and TENS to the salivary glands improve flow and shift the oral microbiome in type 2 diabetes, but evidence is preliminary. PICO summary and commentary.
Clinical Context Type 2 diabetes approximately doubles the risk of dementia and cognitive decline. Diabetic cognitive impairment represents a spectrum…
A clamp study finds tirzepatide preserves the glucagon defence against hypoglycaemia but delays cortisol/noradrenaline and lowers symptom scores, while awareness is unchanged. PICO summary and commentary.
Summary: In patients with type 2 diabetes, stratified by ApoE genotype (E2/E3, E3/E3, E3/E4, and E4/E4 carriers), flaxseed oil supplementation…
An open-label RCT finds 24 g/day fibre cereal improves the FIB-4 fibrosis index and HbA1c in type 2 diabetes with fatty liver, without weight change. PICO summary and commentary.
A 5-week RCT finds aquatic exercise improves blood pressure and function within-group in type 2 diabetes, but without significant differences versus controls. PICO summary and commentary.
Editor’s note: the source article has been retracted and its findings are not reliable. This page is retained for transparency only and should not guide clinical decisions.
An open-label RCT finds adding sitagliptin to standard care improves diabetic foot ulcer healing and raises endothelial progenitor cells, though healing time only trended shorter. PICO summary and commentary.
A 12-month study finds adolescents with poorly controlled type 1 diabetes have low bone density, but glycaemic change does not correlate with bone, while IGF-1 does. PICO summary and commentary.