Clinical Context Charcot neuroarthropathy (CN) is a devastating complication of peripheral neuropathy, most commonly occurring in diabetes. Progressive bone destruction,…
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Clinical Context Gestational diabetes mellitus (GDM) affects 6-15% of pregnancies and is increasing in prevalence alongside the obesity epidemic. GDM…
Clinical Context SGLT2 inhibitors have demonstrated cardiovascular benefits that aren’t fully explained by glucose lowering alone. Standard lipid panels (LDL-C,…
Clinical Context Pregnancy in type 1 diabetes (T1D) requires meticulous glycemic management. Insulin requirements increase dramatically across gestation—typically 50-100% above…
Summary: In 126 pregnant women with type 1 diabetes, metformin (titrated to 1000 mg twice daily) as adjunct to standard…
Clinical Context Patients with diabetes undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) face a therapeutic dilemma: they have…
Clinical Context The transition from pediatric to adult diabetes care represents one of the most vulnerable periods for young people…
Summary: In adults with HFpEF (EF ≥50%), obesity (BMI ≥30 kg/m²), stratified by presence or absence of type 2 diabetes…
Clinical Context Heart failure with preserved ejection fraction (HFpEF) represents approximately half of all heart failure cases and has proven…
Summary: In adults with uncontrolled type 2 diabetes in China, a mobile app-based intervention significantly improved HbA1c and systolic blood…