Clinical Context Chronic low-grade inflammation is increasingly recognized as a central driver of metabolic disease progression. In obesity and prediabetes,…
Browsing: PICO
An analysis of the overall-negative MIND diet trial finds a cognitive benefit only in older adults with BMI 35 or above, a hypothesis-generating subgroup signal. PICO summary and commentary.
Clinical Context Pediatric type 1 diabetes management is notoriously difficult, with most children and adolescents failing to achieve glycemic targets.…
An RCT finds family-centred foot-care training improves knowledge, practice, and support in diabetes, with no ulcers in the intervention group versus 8% control. PICO summary and commentary.
Clinical Context Diabetic foot ulcers (DFUs) represent one of the most devastating and preventable complications of diabetes. In India, where…
Clinical Context Diabetic peripheral neuropathy affects up to 50% of patients with diabetes, and painful diabetic neuropathy (PDN) develops in…
A secondary analysis finds diabetes app users still average only 17 g/day fibre over a year, below target, with no link to HbA1c, suggesting basic app feedback is not enough. PICO summary and commentary.
A small CGM crossover study finds 30 g/day defatted fenugreek flakes reduces 24-hour glucose excursions and variability in type 2 diabetes. PICO summary and commentary.
Clinical Context Hypoglycemia poses particular dangers in elderly patients with diabetes. The physiological warning symptoms that alert younger patients to…
Summary: In elderly individuals with type 2 diabetes at risk of hypoglycemia at outpatient diabetes clinics in Jordan, the SUGAR…