A pilot RCT finds prebiotic inulin enriches SCFA-producing gut bacteria but does not improve HbA1c in Indian children with type 1 diabetes. PICO summary and expert commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A three-arm RCT shows adding a high-protein, low-GI diet to training cuts IL-6 and hs-CRP and improves insulin sensitivity in men with abdominal obesity. PICO summary and commentary.
A qualitative study finds US Dietary Guideline patterns lack cultural relevance for African American adults at risk of type 2 diabetes. PICO summary and expert commentary for clinicians.
An RCT finds adding a ketogenic diet to dulaglutide improves glucose, lipids, and insulin resistance in type 2 diabetes. PICO summary and clinical expert commentary.
An RCT finds water delivery plus parental coaching shifts beverage habits but not BMI in youth on antipsychotics. PICO summary and expert commentary for clinicians.
An RCT finds low-carb and Mediterranean diets do not significantly alter bone turnover markers in young people with type 1 diabetes. PICO summary and expert commentary.
A Lancet phase 2 RCT finds once-weekly semaglutide 2.4 mg reduces heavy drinking days in alcohol use disorder with obesity. PICO summary and expert commentary for clinicians.
An RCT finds a structured lifestyle-based programme improves health behaviours and beliefs in type 2 diabetes, though without glycaemic endpoints. PICO summary and expert commentary.
A crossover nutrigenomics trial finds elderberry juice broadens meal-responsive gene expression in overweight adults, but measures no clinical endpoints. PICO summary and commentary.
A cluster RCT finds peer coaching boosts engagement with weight-management services but misses its 12-month weight endpoint. PICO summary and expert commentary for clinicians.