An RCT finds fixed-intensity combined training reduces the visceral adiposity index more than progressive training in obesity, without changing metabolic phenotype. PICO summary and commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
An RCT finds parent-based lifestyle change reduces BMI in preschoolers, while salivary AMY1 copy number does not predict response. PICO summary and expert commentary.
A baseline report from a Kenyan fermented-foods trial finds heavy cardiometabolic risk clustering in prediabetes; the intervention effect is not yet tested. PICO summary and commentary.
A 12-month RCT finds curcumin 1500 mg daily reduces liver fat, stiffness, and HbA1c in obese type 2 diabetes with MASLD. PICO summary and expert commentary for clinicians.
The LIFE-Moms analysis finds lifestyle counselling slows but does not reverse the activity decline in pregnant women with obesity. PICO summary and expert commentary.
An RCT secondary analysis finds probiotics plus omega-3 do not significantly improve beta-cell function versus placebo in type 2 diabetes. PICO summary and expert commentary.
An RCT finds a culturally tailored South Asian calorie-restriction diet produces modest short-term weight loss in young adults. PICO summary and expert commentary.
A small RCT finds flaxseed oil reduces platelet aggregability but not other risk markers in type 2 diabetes, with no ApoE genotype effect. PICO summary and expert commentary.
A feasibility analysis finds a culturally tailored dietary intervention engages diverse women with gestational diabetes equally, but does not change measured intake. PICO summary and commentary.
A secondary analysis of the BEFORE THE BEGINNING trial finds preconception lifestyle change does not reduce macrosomia or neonatal adiposity. PICO summary and expert commentary.