Summary:
In men with abdominal obesity, aerobic-resistance exercise combined with a high-protein, low-glycemic index diet significantly reduced inflammatory markers (IL-6 and hs-CRP), improved adiponectin levels, insulin sensitivity (FG/I), and body composition (visceral fat, total fat, BAI), and lowered atherogenic risk (CRI II) compared to exercise alone or no intervention, though it was associated with increased dietary fiber and protein intake without reported adverse effects.
| PICO | Description |
|---|---|
| Population | Adult men (mean age 34.7 ± 5.5 years) with abdominal obesity (BMI 32.0 ± 3.9, WC 110.3 ± 8.5 cm). |
| Intervention | Aerobic-resistance training combined with an ad libitum high-protein, low-glycemic index carbohydrate diet (EDG group). |
| Comparison | Exercise-only group (EG) and control group without interventions (CG). |
| Outcome | The combined intervention (EDG) led to significant reductions in IL-6 (-48%), hs-CRP (-30%), insulin resistance FG/I (p=0.02), CRI II (p=0.01), abdominal fat ABD/BM (p<0.01), total fat BF/BM (p<0.01), and body adiposity index (p=0.02), and increased adiponectin by 15% (p=0.02) and FFM/BM (p<0.01). These improvements were more substantial than those achieved by exercise alone. |
Source: Karol Makiel, et al. “Effects of Aerobic-Resistance Training and Nutritional Intervention on Adiponectin, Interleukin-6, and hs-CRP Concentrations in Men with Abdominal Obesity—A Randomized Controlled Trial.” Read article here.
