Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A small randomised study finds dietary management reduces quantitative thyroid MRI inflammation markers and antibodies in Hashimoto's thyroiditis, though the diet is unspecified. PICO summary and commentary.
A secondary analysis finds prenatal exercise blunts the gestational rise in resting maternal lactate, most in women with overweight or obesity. PICO summary and expert commentary.
A small single-blind RCT (n=60) found a family-centered empowerment program raised diabetes acceptance and self-management questionnaire scores versus usual care, with no glycaemic outcomes measured. PICO summary and expert commentary.
A small pilot randomised trial (n=30) testing whether an 8-week integrated intensive exercise protocol improves body composition, functional capacity and quality of life in young adults with obesity versus diet plus brisk walking. PICO summary and expert commentary.
A published BMJ Open study protocol for a planned randomised controlled trial of a COM-B-based exercise intervention in prefrail older adults with diabetes; no efficacy results are reported. PICO summary and expert commentary.
A prespecified secondary analysis of a 12-week randomised trial found time-restricted eating did not change sleep, mood, or quality of life versus usual care in adults with overweight or obesity. PICO summary and expert commentary.
A randomised waitlist-controlled trial of a 10-week whole-food plant-based community programme in a predominantly Maori cohort: weight fell by 3.3 kg versus control, but HbA1c, cholesterol and waist changes were not significant. PICO summary and expert commentary.
A small 12-week randomized controlled trial in male recreational athletes with type 2 diabetes found that only the combined diet plus exercise arm improved both glycemic and body-composition markers, with small effect sizes. PICO summary and expert commentary.
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