A small 12-week randomized controlled trial in male recreational athletes with type 2 diabetes found that only the combined diet plus exercise arm improved both glycemic and body-composition markers, with small effect sizes. PICO summary and expert commentary.
Browsing: Type 2 Diabetes
Landmark trials and recent evidence on type 2 diabetes management, glucose-lowering therapy, and outcomes.
A single-centre randomised trial testing home telemedicine with Health Belief Model education against conventional care for HbA1c in older adults with type 2 diabetes. PICO summary and expert commentary.
A 93-patient RCT found structured exercise after gastric bypass did not improve the primary 2-hour glucose endpoint but added modest weight and fat-mass loss. PICO summary and expert commentary.
A randomised non-inferiority trial of a low-energy total diet replacement programme in people with type 2 diabetes at high eating-disorder risk: PICO summary and expert commentary.
An observational comparison of 76 Colorado primary care practices found that having a diabetes care and education specialist was strongly associated with choosing self-paced CGM implementation over a virtual referral service. PICO summary and expert commentary.
An exploratory secondary analysis of two Phase 2 trials reports that oral orforglipron lowered blood pressure, LDL cholesterol, triglycerides, ApoB, ApoC3, and hsCRP versus placebo, though no cardiovascular events were measured. PICO summary and expert commentary.
A nested qualitative process evaluation of the SuMMiT-D SMS intervention found patients described holistic, context-dependent benefits rather than measured adherence gains. PICO summary and expert commentary.
A secondary analysis of a Swedish RCT links higher engagement with a smartphone dietary-education app to modest dietary improvements, with no significant cardiometabolic marker changes, in adults with type 2 diabetes. PICO summary and expert commentary.
A multicentre open-label RCT testing whether 12-month mHealth home telemonitoring improves blood pressure and HbA1c versus standard care in older adults with hypertension and type 2 diabetes. PICO summary and expert commentary.
A 58-patient single-site implementation RCT of the community-health-worker-led TIME programme for uninsured Hispanic adults with type 2 diabetes, with PICO summary and expert commentary.