Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A single-centre Chinese RCT found a mobile health lifestyle programme modestly reduced gestational weight gain and fasting glucose in overweight or obese pregnant women, with no effect on gestational diabetes incidence. PICO summary and expert commentary.
A randomised non-inferiority trial of a low-energy total diet replacement programme in people with type 2 diabetes at high eating-disorder risk: PICO summary and expert commentary.
An observational comparison of 76 Colorado primary care practices found that having a diabetes care and education specialist was strongly associated with choosing self-paced CGM implementation over a virtual referral service. PICO summary and expert commentary.
A published protocol for the D-REM pragmatic randomized trial testing community paramedic home visits versus usual care in adults with diabetes and level 3 hypoglycemia. No outcomes are reported yet. PICO summary and expert commentary.
An exploratory secondary analysis of two Phase 2 trials reports that oral orforglipron lowered blood pressure, LDL cholesterol, triglycerides, ApoB, ApoC3, and hsCRP versus placebo, though no cardiovascular events were measured. PICO summary and expert commentary.
A nested qualitative process evaluation of the SuMMiT-D SMS intervention found patients described holistic, context-dependent benefits rather than measured adherence gains. PICO summary and expert commentary.
A secondary analysis of the FINGER lifestyle trial found that baseline dysglycaemia, especially OGTT-derived measures, was associated with less favourable cognitive and brain changes, while HbA1c showed mixed results. PICO summary and expert commentary.
A retrospective secondary analysis clustered app-usage data from 328 pregnant women in a gestational diabetes mHealth trial into three engagement types, with most classified as moderate users. PICO summary and expert commentary.
A secondary analysis of a Swedish RCT links higher engagement with a smartphone dietary-education app to modest dietary improvements, with no significant cardiometabolic marker changes, in adults with type 2 diabetes. PICO summary and expert commentary.
A multicentre open-label RCT testing whether 12-month mHealth home telemonitoring improves blood pressure and HbA1c versus standard care in older adults with hypertension and type 2 diabetes. PICO summary and expert commentary.
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