Does Dapagliflozin Improve Heart Blood Flow Long-Term in Type 2 Diabetes?
The DAPAHEART follow-up finds 4 years of dapagliflozin improves coronary flow reserve and reduces epicardial fat in type 2 diabetes. PICO summary and expert commentary.
Hormone Insight Editorial Team
Clinical archive
Can Placenta-Derived Cells Heal Diabetic Foot Ulcers with Poor Circulation?
A phase 2 RCT finds placenta-derived cells improve diabetic foot ulcer closure in the peripheral artery disease subgroup. PICO summary and expert commentary for clinicians.
Can Sitagliptin Help Heal Diabetic Foot Ulcers?
An RCT finds adding sitagliptin to standard care improves diabetic foot ulcer healing via an EPC/SDF-1α mechanism. PICO summary and expert commentary for clinicians.
Is the Confident Moves Online Program Effective and Feasible for Adults with Obesity?
A feasibility pilot finds the Confident Moves online programme engages adults with obesity and nudges activity, but measures no weight outcomes. PICO summary and expert commentary.
Can Aquatic Exercise Improve Blood Pressure and Fitness in People with Type 2 Diabetes?
An RCT finds five weeks of aquatic exercise improves blood pressure and fitness within-group in type 2 diabetes, but shows no advantage over control. PICO summary and commentary.
Does Fixed-Intensity Training Reduce Visceral Fat in Obesity Better Than Progressive Training?
An RCT finds fixed-intensity combined training reduces the visceral adiposity index more than progressive training in obesity, without changing metabolic phenotype. PICO summary and commentary.
Can Dexmedetomidine Help Control Blood Sugar During Surgery in Type 2 Diabetes?
An RCT finds low-dose dexmedetomidine steadies perioperative glucose in diabetic surgery while higher doses worsen it. PICO summary and expert commentary for clinicians.
Is the Salivary AMY1 Gene Linked to Childhood Obesity and Lifestyle Change Success?
An RCT finds parent-based lifestyle change reduces BMI in preschoolers, while salivary AMY1 copy number does not predict response. PICO summary and expert commentary.
Can 660 nm laser therapy help heal diabetic foot ulcers?
An RCT finds 660 nm photobiomodulation reduces diabetic foot ulcer area but does not beat 904 nm; ≥8 J/cm² works best. PICO summary and expert commentary for clinicians.
Can Family-Based Team Care Improve Outcomes in Hypertension and Diabetes?
An RCT finds interdisciplinary care with family empowerment improves blood pressure, glucose, and quality of life in comorbid hypertension and diabetes. PICO summary and commentary.