Clinical Context Type 2 diabetes approximately doubles the risk of dementia and cognitive decline. Diabetic cognitive impairment represents a spectrum…
Browsing: PICO
Structured PICO summaries for doctors and healthcare professionals, covering population, intervention, comparison, outcomes, expert commentary, and references across diabetes, endocrinology, obesity, and cardiometabolic medicine.
A clamp study finds tirzepatide preserves the glucagon defence against hypoglycaemia but delays cortisol/noradrenaline and lowers symptom scores, while awareness is unchanged. PICO summary and commentary.
Summary: In patients with type 2 diabetes, stratified by ApoE genotype (E2/E3, E3/E3, E3/E4, and E4/E4 carriers), flaxseed oil supplementation…
An open-label RCT finds 24 g/day fibre cereal improves the FIB-4 fibrosis index and HbA1c in type 2 diabetes with fatty liver, without weight change. PICO summary and commentary.
A 5-week RCT finds aquatic exercise improves blood pressure and function within-group in type 2 diabetes, but without significant differences versus controls. PICO summary and commentary.
Editor’s note: the source article has been retracted and its findings are not reliable. This page is retained for transparency only and should not guide clinical decisions.
An open-label RCT finds adding sitagliptin to standard care improves diabetic foot ulcer healing and raises endothelial progenitor cells, though healing time only trended shorter. PICO summary and commentary.
A 12-month study finds adolescents with poorly controlled type 1 diabetes have low bone density, but glycaemic change does not correlate with bone, while IGF-1 does. PICO summary and commentary.
An RCT finds higher-temperature (44-46C) moxibustion improves cognition and HbA1c more than lower temperatures in type 2 diabetes, though fasting glucose was unchanged. PICO summary and commentary.
A four-arm RCT finds exercise plus broccoli sprouts improves apolipoproteins in men with type 2 diabetes, but the benefit is mainly exercise-driven. PICO summary and commentary.