A four-arm RCT finds only low-dose dexmedetomidine improves perioperative glucose in type 2 diabetes, while higher doses raise it, showing a dose-dependent effect. PICO summary and commentary.
Browsing: PICO
Structured PICO summaries for doctors and healthcare professionals, covering population, intervention, comparison, outcomes, expert commentary, and references across diabetes, endocrinology, obesity, and cardiometabolic medicine.
Summary: In patients with suboptimal glycemic control, an eHealth application module significantly improved glycemic control compared to usual care without…
An RCT finds an eHealth app improves HbA1c at 4 months in older diabetes patients, but usage declines by 8 months, raising durability concerns. PICO summary and commentary.
Clinical Context Dexamethasone is widely used perioperatively for prevention of postoperative nausea and vomiting (PONV), reduction of inflammation and edema,…
A double-blind RCT finds a single intraoperative dexamethasone dose raises glucose significantly but below 180 mg/dL in diabetic and non-diabetic patients, supporting nausea prophylaxis. PICO summary and commentary.
Summary: In adults diagnosed with type 2 diabetes receiving standard medical treatment in China, Sanxiao Jiuzhi Gong (SJG) exercise therapy…
A single-centre RCT reports large glycaemic gains from qigong (Sanxiao Jiuzhi Gong) in type 2 diabetes, but the implausibly large effect size warrants caution. PICO summary and commentary.
A double-blind RCT finds a single high dose of vitamin D before an ultramarathon favourably shifts bone turnover markers, though mega-dosing remains experimental. PICO summary and commentary.
Summary: In patients with type 2 diabetes exhibiting reduced salivary gland function and associated oral symptoms, low-level laser therapy combined…
A very small interim RCT analysis finds laser and TENS to the salivary glands improve flow and shift the oral microbiome in type 2 diabetes, but evidence is preliminary. PICO summary and commentary.