Clinical Context Type 2 diabetes is fundamentally a disease of progressive beta-cell failure against a backdrop of insulin resistance. While…
Browsing: PICO
Summary: In adults diagnosed with type 2 diabetes mellitus enrolled in a randomized controlled trial comparing exercise modalities, combined aerobic…
Clinical Context Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) affects up to 70-80% of patients with type 2 diabetes…
Clinical Context The gut microbiome has emerged as a significant player in metabolic health. Patients with type 2 diabetes consistently…
Clinical Context Randomized controlled trials establish efficacy under ideal conditions, but real-world effectiveness may differ due to patient selection, adherence…
Clinical Context Type 2 diabetes is paradoxically associated with increased fracture risk despite often-normal or even elevated bone mineral density…
Summary: In patients with comorbid hypertension and diabetes, an interdisciplinary collaborative care model combined with family empowerment based on the…
Clinical Context Diabetic foot ulcers (DFUs) affect approximately 15-25% of people with diabetes during their lifetime and are the leading…
Clinical Context Perioperative hyperglycemia and glucose variability are independent predictors of poor outcomes after cardiac surgery, including increased mortality, sternal…
Summary: In patients with diabetic foot ulcers, including those with peripheral artery disease, intramuscular human placenta-derived cells (PDA-002) at doses…
