An RCT finds exogenous ketone salts produce no body-composition advantage over placebo on a hypocaloric diet. PICO summary and expert commentary.
Browsing: Metabolism
Obesity and weight management, metabolic syndrome and insulin resistance, MASLD/fatty liver, and nutrition and lifestyle evidence.
A health-economic evaluation finds a school-based app obesity-prevention programme cost-effective in Chinese primary schools. PICO summary and expert commentary.
A small crossover trial finds a BCAA, HMB, and zinc supplement increases muscle mass and lowers inflammation in dialysis patients, but not physical performance. PICO summary and commentary.
The large D-Health trial finds monthly vitamin D does not prevent hypertension, high cholesterol, or type 2 diabetes in replete older adults. PICO summary and expert commentary.
A three-arm trial finds a non-diet, person-centred approach matches a hypocaloric diet on metabolic measures while improving mental well-being in women with obesity. PICO summary and commentary.
A four-arm trial finds combined training plus fisetin most improves adipokines and lipids in men with obesity, with exercise the main driver. PICO summary and commentary.
A crossover trial finds honey-sweetened yogurt does not change the primary inflammatory marker in postmenopausal women, with only a single secondary signal. PICO summary and commentary.
A large BMJ trial finds vitamin D before IVF raises blood levels but does not improve live birth rates in women with PCOS. PICO summary and expert commentary.
An RCT finds the weekly GLP-1 agonist PEG-Loxe produces large dose-dependent weight loss in super-obese patients with type 2 diabetes. PICO summary and expert commentary.
A feasibility study finds preliminary but non-significant physiological responses to weight stigma in women with obesity, while proving the method workable. PICO summary and commentary.