A preschool trial finds body composition improved over time with game-based activity, but moderate-to-vigorous activity did not significantly beat light activity. PICO summary and commentary.
Browsing: Obesity & Weight Management
Evidence summaries for obesity and weight management, including lifestyle trials, pharmacotherapy, bariatric/metabolic outcomes, cardiometabolic risk, and long-term safety.
A 6-month school-based MyBFF@school program improved fasting insulin, HOMA-IR, and HDL-C versus standard schooling in overweight Malaysian children, though BMI still rose. PICO summary and expert commentary.
A triple-blind RCT finds cinnamon supplementation does not significantly reduce weight or BMI in type 2 diabetes. PICO summary and expert commentary.
A single-centre Egyptian RCT testing whether adding Islamic intermittent fasting to lifestyle modification improves metabolic syndrome markers, with PICO summary and expert commentary.
A four-arm trial finds combination aerobic-resistance exercise is the only programme to improve objective sleep in type 2 diabetes, alongside abdominal fat loss. PICO summary and commentary.
A small pilot randomised trial (n=30) testing whether an 8-week integrated intensive exercise protocol improves body composition, functional capacity and quality of life in young adults with obesity versus diet plus brisk walking. PICO summary and expert commentary.
A prespecified secondary analysis of a 12-week randomised trial found time-restricted eating did not change sleep, mood, or quality of life versus usual care in adults with overweight or obesity. PICO summary and expert commentary.
A randomised waitlist-controlled trial of a 10-week whole-food plant-based community programme in a predominantly Maori cohort: weight fell by 3.3 kg versus control, but HbA1c, cholesterol and waist changes were not significant. PICO summary and expert commentary.
Clinical Context GLP-1 receptor agonists produce substantial weight loss, but the mechanisms underlying this effect have been debated. Is weight…
Clinical Context Heart failure with preserved ejection fraction (HFpEF) represents one of the most challenging conditions in cardiovascular medicine. Unlike…