An open-label multicentre RCT in 155 women with PCOS found that a letrozole ovulation regimen for frozen-thawed embryo transfer achieved clinical pregnancy rates comparable to a programmed regimen while requiring simpler luteal support. PICO summary and expert commentary.
Browsing: Endocrinology
A small randomised study finds dietary management reduces quantitative thyroid MRI inflammation markers and antibodies in Hashimoto’s thyroiditis, though the diet is unspecified. PICO summary and commentary.
Summary: In 40 patients with confirmed Hashimoto’s thyroiditis (elevated antibodies and characteristic features), structured dietary intervention targeting thyroid health and…
A small three-arm trial finds stem cells plus shock wave therapy outperform either alone for diabetic erectile dysfunction, a proof-of-concept result. PICO summary and commentary.
A secondary analysis finds prenatal exercise blunts the gestational rise in resting maternal lactate, most in women with overweight or obesity. PICO summary and expert commentary.
Three-year REAL4 extension data on once-weekly somapacitan versus daily growth hormone in children with growth hormone deficiency, with PICO summary and expert commentary.
A randomized controlled trial found progestin-primed ovarian stimulation and the GnRH antagonist protocol produced statistically similar euploidy rates in PGT-A cycles. PICO summary and expert commentary.
A 103-patient randomized trial tested an extra 25 mcg of levothyroxine during Ramadan against standard weight-based dosing in hypothyroidism. PICO summary and expert commentary.
A 12-week randomized controlled trial found light-to-moderate aerobic walking produced no significant between-group change in bone turnover markers versus inactive controls in postmenopausal osteopenia, with functional gains reported. PICO summary and expert commentary.
A 43-patient single-centre open-label RCT found clinical pharmacist review reduced drug-related problems within the intervention arm but showed no significant between-group difference in overall levothyroxine adherence. PICO summary and expert commentary.