A manufacturer-sponsored randomized trial of a low-glycemic-index/slow-digesting carbohydrate product in obese pregnant women found no effect on the primary glycemic outcomes. PICO summary and expert commentary.
Browsing: Endocrinology
Clinical Context Pituitary adenomas are the third most common intracranial tumor, affecting up to 20% of the population based on…
A three-arm RCT finds moxibustion plus low-dose tadalafil outperforms either alone for diabetic erectile dysfunction, in an unblinded single-centre setting. PICO summary and commentary.
An RCT finds Wuziyuye Decoction improves sperm motility and concentration over L-carnitine in diabetic men, but without improving pregnancy rates. PICO summary and commentary.
Clinical Context Type 2 diabetes affects male fertility through multiple interconnected mechanisms. Chronic hyperglycemia generates oxidative stress that damages sperm…
Clinical Context Erectile dysfunction (ED) affects 35-75% of men with diabetes mellitus, with prevalence increasing with diabetes duration, poor glycemic…
A randomised study finds pure endoscopic pituitary surgery improves goal achievement and pituitary function preservation versus microscopic, with similar long-term outcomes. PICO summary and commentary.
A 50-year follow-up of the Auckland Steroid Trial finds no transgenerational metabolic harm in the grandchildren of antenatal-steroid pregnancies. PICO summary and commentary.
An RCT finds adding semaglutide to metformin improves weight, testosterone, and natural pregnancy rates in women with PCOS. PICO summary and expert commentary.
A randomised comparison finds gadobutrol non-inferior to meglumine gadoterate for pituitary DCE-MRI but with a higher Kep to recognise, not a clear superiority. PICO summary and commentary.