A 6-month school-based MyBFF@school program improved fasting insulin, HOMA-IR, and HDL-C versus standard schooling in overweight Malaysian children, though BMI still rose. PICO summary and expert commentary.
Browsing: Diabetes Prevention
A secondary analysis of a gestational-diabetes RCT (122 dyads) found cord-blood lipids, but not maternal lipids after correction, were associated with children’s beta-cell function at age 9. PICO summary and expert commentary.
The NIGOHealth randomized trial found no effect of a low glycaemic index/slow digesting carbohydrate product on primary maternal glycaemia outcomes in obese pregnant women, with only a small secondary HbA1c difference. PICO summary and expert commentary.
A single-centre Chinese RCT found a mobile health lifestyle programme modestly reduced gestational weight gain and fasting glucose in overweight or obese pregnant women, with no effect on gestational diabetes incidence. PICO summary and expert commentary.
A secondary analysis of the FINGER lifestyle trial found that baseline dysglycaemia, especially OGTT-derived measures, was associated with less favourable cognitive and brain changes, while HbA1c showed mixed results. PICO summary and expert commentary.
A retrospective secondary analysis clustered app-usage data from 328 pregnant women in a gestational diabetes mHealth trial into three engagement types, with most classified as moderate users. PICO summary and expert commentary.
A small open-label RCT testing whether real-time CGM feedback added to individualized nutrition therapy improves diet and sleep in prediabetes with overweight or obesity. PICO summary and expert commentary.
A small single-centre randomised trial testing weight-lowering hypoglycaemic agents plus a high-protein diet and moderate exercise against standard care for diabetes remission in adults with obesity. PICO summary and expert commentary.
A small 12-week factorial feeding trial in prediabetes found that shifting unsaturated fat intake to lunch rather than dinner improved insulin-sensitivity indices, while the primary postprandial glucose outcome was null. PICO summary and expert commentary.
A TrialNet post hoc analysis in 40 high-risk relatives found oral insulin favourably shifted a combined glucose and C-peptide surrogate (p=0.037), not a proven delay in diabetes onset. PICO summary and expert commentary.