Summary: In type 2 diabetic stage-II periodontitis patients, non-surgical periodontal therapy with adjunctive hyaluronic acid (HA) gel significantly improved periodontal…
Browsing: Diabetes Complications
Microvascular and macrovascular complications of diabetes: retinopathy, nephropathy, neuropathy, and cardiovascular risk.
Summary: In patients with diabetic erectile dysfunction (ED), high-activity placenta-derived mesenchymal stem cells (hPMSCs) combined with low-intensity extracorporeal shock wave…
A double-blinded RCT in 162 adults found wound blotting-guided biofilm management improved the DMIST wound score and biofilm removal over three weeks in diabetic foot ulcers, though only surrogate endpoints were measured. PICO summary and expert commentary.
A MEAD post-hoc analysis finds the dexamethasone implant doubles diabetic macular oedema resolution, with thicker baseline maculae resolving more slowly. PICO summary and commentary.
A secondary analysis of the VA NEPHRON-D cohort found that higher baseline urinary EGF and uromodulin were independently associated with a lower risk of diabetic kidney disease progression. PICO summary and expert commentary.
A randomized trial testing whether a patient previsit activation handout, added to physician academic detailing, increases diabetes medication deprescribing in adults 75 and older. PICO summary and expert commentary.
A randomized crossover trial found the cardiac output response to 3-hydroxybutyrate was blunted by roughly 80% in type 1 diabetes, with no gain in systolic function and reduced ventricular work efficiency. PICO summary and expert commentary.
An open-label RCT finds N-acetylcysteine speeds the fall in inflammatory markers in diabetic foot osteomyelitis, though clinical outcomes were not measured. PICO summary and commentary.
A small RCT suggests low-dose atorvastatin may aid anti-VEGF therapy for diabetic macular edema more than high-dose, though key endpoints were non-significant. PICO summary and commentary.
A small phase 2 trial finds adding dexamethasone to aflibercept improves diabetic macular edema outcomes with no IOP rise. PICO summary and expert commentary.